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A further 1,018 coronvirus patients have died in UK hospitals.
There have been 884 new fatalities in English hospitals, 64 in Scotland, 54 in Wales and 16 in Northern Ireland.
The latest deaths are far higher than the 819 fatalities recorded last Thursday.
The new figures show that the south-east was hardest-hit, with 209 deaths.
London came second with 185 fatalities, followed by 175 in the Midlands, 117 in the east of England, 80 in the north-east and Yorkshire.
The north-west recorded 80 deaths, while the south-west announced 38.
The UK recorded its biggest daily rise in Covid deaths in hospitals, care homes and other settings yesterday, with 1,546 fatalities announced.
Hospital admissions are spiking in England
(Image: Press Association Images)
Covid hospital admissions hit record high and cases are still rising among over-80s
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While the DoH officially recorded a total of 84,767 deaths within 28 days of a positive test, analysis of official data shows more than 100,000 deaths involving coronavirus have now occurred in the UK.
As the second wave of Covid-19 tears across the UK, London Mayor Sadiq Khan reveals more than 10,000 Londoners have now died with Covid-19.
"Many of the families will be listening to this programme now and they're in my thoughts and prayers… it's heartbreaking it's come to this," Mr Khan told LBC.
Doctors have warned of the huge strain they are working under as admissions spike
(Image: Getty Images)
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"This epidemic is far worse than it was in spring, the pressures on the NHS are far higher, yet the lockdown measures are much lighter."
Mr Khan said he and the leader of London Councils, Georgie Gould, have written to the Prime Minister "pleading with him to have additional restrictions on our city".
"We think that's the best way to save lives and stop the NHS being overwhelmed," he added.
Yesterday the NHS revealed a record number of deaths in hospital settings, with a further 1,176 fatalities recorded.
There were 1,012 deaths in hospitals England, 79 in Scotland, 66 deaths in Wales and 19 in Northern Ireland.
Last Wednesday recorded hospital deaths across the UK were up by 831.